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Please use this identifier to cite or link to this item: http://repositorio.insp.mx:8080/jspui/handle/20.500.12096/8644
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dc.coverage.spatialnacional-
dc.creatorFarías Serra, Paulina-
dc.date.accessioned2024-04-29T22:42:32Z-
dc.date.available2024-04-29T22:42:32Z-
dc.date.issued2022-
dc.identifier.issn1660-4601-
dc.identifier.urihttps://www.mdpi.com/1660-4601/19/20/13020/pdf?version=1665630552-
dc.identifier.urihttps://doi.org/10.3390/ijerph192013020-
dc.identifier.urihttp://repositorio.insp.mx:8080/jspui/handle/20.500.12096/8644-
dc.description.abstractAbstract Lead (Pb), mercury (Hg), and manganese (Mn) are neurotoxic, but little is known about the neurodevelopmental effects associated with simultaneous prenatal exposure to these metals. We aimed to study the associations of Pb, Hg, and Mn prenatal levels (jointly and separately) with neurodevelopment in the first year of life. Methods: Pb, Hg, and Mn blood lead levels were measured in 253 pregnant women. Their offsprings neurodevelopment was assessed through the Bayley Scale of Infant Development III at one, three, six, and twelve months. The metals mean blood levels (gL) were Pb 11.2, Hg 2.1, and Mn 10.2. Mean language, cognitive, and motor development scores of the infants at each age were between low-average and average. Multilevel models results showed that language development coefficients of the offspring decreased by 1.5 points per 1 gdL increase in maternal blood lead levels (p 0.002); the magnitude of the aforementioned association increased in children with maternal blood Mn 9.6 gL ( -1.9, p 0.003) or Hg 1.9 gL ( -1.6, p 0.013). Cognitive and motor development had negative associations with maternal blood Pb levels; the latter was statistically significant when the interaction term between Pb, Mn, and Hg was included ( -0.037, p 0.03). Prenatal exposure to low Pb levels may impair infants neurodevelopment in the first year of life, even more so if they are exposed to Hg or deficient in Mn.-
dc.formatpdf-
dc.languageeng-
dc.publisherPMC-
dc.rightsinfo:eu-repo/semantics/openAccess-
dc.rightshttp://creativecommons.org/licenses/by-nc-nd/4.0-
dc.subjectchildren; co-exposure; lead; manganese; mercury; neurodevelopment; prenatal.-
dc.titlePrenatal Co-Exposure to Manganese, Mercury, and Lead, and Neurodevelopment in Children during the First Year of Life-
dc.typeinfo:eu-repo/semantics/article-
dc.subject.ctiinfo:eu-repo/classification/cti/3-
dc.creator.orcidorcid/0000-0002-2034-6389;Farías Serra, Paulina-
dc.creator.orcidorcid/0000-0002-2034-6389;Farías Serra, Paulina-
dc.creator.orcidorcid/0000-0003-0539-8495;Hernández-Bonilla , David-
dc.creator.orcidorcid/0000-0002-6734-0486;Riojas-Rodriguez, Horacio-
dc.creator.orcidorcid/0000-0002-7967-0570;Schnaas, Lourdes-
dc.creator.orcidorcid/0000-0003-4507-9237;Texcalac Sangrador, José Luis-
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