DSpace JSPUI


DSpace preserves and enables easy and open access to all types of digital content including text, images, moving images, mpegs and data sets

Learn More

Please use this identifier to cite or link to this item: http://repositorio.insp.mx:8080/jspui/handle/20.500.12096/8464
Full metadata record
DC FieldValueLanguage
dc.coverage.spatialnacional-
dc.creatorCarnalla, Martha-
dc.date.accessioned2024-04-29T22:42:07Z-
dc.date.available2024-04-29T22:42:07Z-
dc.date.issued2021-
dc.identifier.issn1660-4601-
dc.identifier.urifile:///C:/Users/atalani.REDINSP/Downloads/ijerph-18-09058-v2.pdf-
dc.identifier.urihttps://doi.org/10.3390/ijerph18179058.-
dc.identifier.urihttp://repositorio.insp.mx:8080/jspui/handle/20.500.12096/8464-
dc.description.abstractAbstract The causes of the broad spectrum of severity in COVID-19 are unknown. A protective effect through humoral immunity from previous infections by viruses of the SARS-CoV-2 family could explain a mild form of this disease. This study aimed to address whether the presence of antibodies against human seasonal coronaviruses (HCoVs) could prevent severe manifestations of COVID-19. A cross-sectional study was carried out in 165 participants. The presence of pre-existent antibodies against the seasonal HCoV-OC43, HCoV-HKU1, HCoV-229E, and HCoV-NL63 were detected. From all of the seasonal HCoVs studied, it was only found that being seropositive to HCoV-229E presented an association (p 0.012) with developing mild clinical symptoms of COVID-19 or being asymptomatic. Multinomial regression analysis showed that being seropositive to HCoV-229E is associated with mild or moderate clinical symptoms for COVID-19. Statistical analysis also showed that being female is associated with being asymptomatic for SARS-CoV-2 infection or developing mild COVID-19. A subgroup analysis taking only seropositive to HCoV-229E revealed that females are more likely to develop asymptomatic SARS-CoV-2 infection (OR 27.242, 95 CI 2.092-354.706, p 0.012). Our results suggest that previous infections by HCoV-229E could prevent more serious clinical manifestations of COVID-19, but these are not the only variables that influence this event.-
dc.formatpdf-
dc.languageeng-
dc.publisherPMC PubMed Central-
dc.rightsinfo:eu-repo/semantics/openAccess-
dc.rightshttp://creativecommons.org/licenses/by-nc-nd/4.0-
dc.subjectAntibodies, Viral COVID-19* Coronavirus 229E, Human* Cross-Sectional Studies Female Humans SARS-CoV-2 Substances nan-
dc.titlePotential Protection of Pre-Existent Antibodies to Human Coronavirus 229E on COVID-19 Severity-
dc.typeinfo:eu-repo/semantics/article-
dc.subject.ctiinfo:eu-repo/classification/cti/3-
dc.creator.orcidorcid/0000-0003-1427-2915;Carnalla, Martha-
dc.creator.orcidorcid/0000-0003-4658-0787;Aguilar Guardado, Kathia Liliana-
dc.creator.orcidorcid/0000-0002-0826-9106;Barrientos_Gutierrez, Tonatiuh-
dc.creator.orcidorcid/0000-0002-3183-7255;ESPINOSA ORGANISTA, RAFAELA-
dc.creator.orcidorcid/0000-0002-2920-845X;López Guerrero, Delia Vanessa-
dc.creator.orcidorcid/0000-0001-8090-4103;Montero, Hilda-
dc.creator.orcidorcid/0000-0003-4953-5076;Ortiz-León, María Cristina-
dc.creator.orcidorcid/0000-0001-9284-7775;Pérez-Carreón, Julio Isael-
dc.creator.orcidorcid/0000-0002-4000-5848;RAMOS GARCIA, CELSO-
dc.creator.orcidorcid/0000-0001-7495-426X;Sampieri Ramírez, Clara Luz-
dc.creator.orcidorcid/0000-0003-3437-2622;TRUJILLO RIVERA, ALEJANDRO-
dc.creator.orcidorcid/0000-0002-1162-384X;Varela Cardoso, Miguel-
dc.creator.orcidorcid/0000-0001-9597-127X;ZENTENO_CUEVAS, ROBERTO-
Appears in Collections:Artículos

Files in This Item:
There are no files associated with this item.


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.